DIPHTHERIA "CARRIERS"

Diphtheria carriers and the effect of erythromycin therapy.

One hundred and fourteen Corynebacterium diphtheriae, toxigenic, gravis type, pharyngeal carriers were identified during a diphtheria epidemic in Elgin, Texas. All carriers were treated with erythromycin estolate, 1 g/day in divided doses for 6 days. Serial pharyngeal cultures were obtained in order to monitor the bacteriological response. Seventy-two carriers had positive cultures immediately ...

Preparation and evaluation of chitosan nanoparticles containing Diphtheria toxoid as new carriers for nasal vaccine delivery in mice

 The aim of me present work was to investigate rhe potential utility of nanoparticles made of chitosan (CS) and also CS chemically modified with polyethylene glycol (CS-PEG) as new vehicles for improving na^al vaccine delivery. For mis purpose, diphtheria toxoid (DT) was chosen as a model antigen. DT was entrapped within nanoparticles made of CS of different molecular weight, and also made of C...

Diphtheria

Gentlemen,?I have occasionally heard a man, about to read a paper upon some subject, commence by expressing his sense of his unfitness for the task he has undertaken. I have, I must confess, looked upon this appeal, ad misericordiam, with much suspicion, believing the writer, did he not in his own heart believe himself particularly well-fitted for the work, would not have undertaken it. To-day,...

Diphtheria

Diphtheria Immunization *

AT the beginning of the twentieth century diphtheria occupied a unique position in contrast to other infectious diseases. Its symptoms and course were well known and accurately described, the causal organism definitely recognized, and a specific remedy was available for its treatment, yet in spite of this wealth of scientific knowledge the control and prevention of the disease had proved a comp...